Refereed publications from the Lee Laboratory.
Individuals working in the Lee Lab at the time work was done are indicated in bold.
Smith, D.R. (2009) Unparalleled GC
content in the plastid DNA of Selaginella.
Plant Mol. Biol.
71:627-639. View PDF.
This work was conducted in the laboratory of
R.W. Lee and supported by his NSERC
grant.
Borza, T., Redmond, E.K., Laflamme, M. and Lee R.W. (2009) Mitochondrial DNA in the Oogamochlamys-clade (Chlorophyceae): high GC content and unique genome architecture for green algae. J. Phycol. 45:1323-1334. View PDF.
Smith, D.R. and Lee, R.W. (2009) Nucleotide diversity of the Chlamydomonas reinhardtii plastid genome: addressing the mutational-hazard hypothesis. BMC Evolutionary Biology 9:120. View PDF.
Smith, D.R. and Lee, R.W. (2009) The mitochondrial and plastid genomes of Volvox carteri: bloated molecules rich in repetitive DNA. BMC Genomics 10:132. View PDF.
Smith, D.R. and Lee, R.W. (2008) Nucleotide diversity in the mitochondrial and nuclear compartments of Chlamydomonas reinhardtii: investigating the origins of genome architecture. BMC Evolutionary Biology 8:156. View PDF.
Smith, D.R. and Lee, R.W. (2008) Mitochondrial genome of the colorless green alga Polytomella capuana: a linear molecule with an unprecedented GC content. Mol. Biol. Evol. 25:487-496. View PDF.
Koziol, A.G., Borza, T., Ishida,
K.-I., Keeling, P., Lee, R.W. and D.G. Durnford (2007) Tracing
the evolution of the light-harvesting antennae in chlorophyll
a/b-containing organisms. Plant Physiol.143:1-15
Popescu, C.E and
Lee, R.W. (2007) Mitochondrial genome sequence evolution
in Chlamydomonas. Genetics 175:819-826
View PDF.
Nedelcu, A.M.1, Borza, T.1,
and Lee, R.W. (2006) A Plant-Specific Multigene Family in
the Unicellar Mesostigma Argues for Its Close
Relationship to Streptophyta. Mol. Biol. Evol.
23:1011-1015.
View PDF.
1These authors contributed equally to this work.
Popescu, C.E., Borza, T., Bielawski, J.P. and Lee, R.W. (2006) Evolutionary Rates and Expression Level in Chlamydomonas. Genetics 172:1567-1576 View PDF.
Mallet, M.A. and Lee, R.W. (2006) Identification of three distinct Polytomella lineages based on mitochondrial DNA features. J. Euk. Microbiol. 53: 79-84 View PDF.
Keeling, P.J., Burger, G., Durnford,
D.G., Lang, B.F., Lee, R.W., Pearlman, R.E., Roger, A. J. and
Gray, M.W. (2005) The tree of eukaryotes. Trends Ecol. Evol.
20: 670-676
Borza, T., Popescu, C.E. and Lee, RW. (2005) Multiple metabolic roles for the nonphotosynthetic plastid of the green alga Prototheca wickerhamii. Euk. Cell 4:253-261 View PDF.
Laflamme, M. and
Lee, R.W. (2003) Mitochondrial genome conformation among
CW-group chlorophycean algae. J. Phycol. 39, 213-220
(2003).
View PDF.
Fan, J., Schnare, M.N. and Lee, R.W. (2003) Characterization of fragmented mitochondrial ribosomal RNAs of the colorless green alga Polytomella parva. Nucleic Acids Res. 31: 769-778 View PDF.
Fan, J. and Lee, R.W. (2002) Mitochondrial genome of the colorless green alga Polytomella parva: Two linear DNA molecules with homologous inverted repeat termini. Mol. Biol. Evol. 19:999-1007 View PDF.
Nedelcu, A.M. and Lee, R.W., Lemieux, C., Gray, M.W. and Burger, G. (2000) The complete mitochondrial DNA sequence of Scenedesmus obliquus reflects an intermediate stage in the evolution of the green algal mitochondrial genome. Genome Res. 10:819-831 View PDF.
Nedelcu, A.M. and
Lee, R.W. (1998) Modes and tempos of mitochondrial and
chloroplast genome evolution in Chlamydomonas: a
comparative analysis. In: Rochaix, J.-D., M.
Goldschmidt-Clermont and M. Merchant (Eds.), The Molecular
Biology of Chlamydomonas:
chloroplasts and mitochondria, pp. 63-91, Kluwer Academic
Publishers, The Netherlands.
Nedelcu, A.M. and
Lee, R.W. (1998) A degenerate group II intron in the intronless
mitochondrial genome of Chlamydomonas reinhardtii:
Evolutionary implications. Mol. Biol. Evol.
15:918-922
Nedelcu, A.M. and
Lee, R.W. (1998) Short repetitive sequences in green algal
mitochondrial genomes: Potential roles in mitochondrial genome
evolution. Mol. Biol. Evol. 15:690-701
Nedelcu, A,M (1998)
Contrasting mitochondrial genome organizations and sequence
affiliations among green algae: Potential factors, mechanisms,
and evolutionary scenarios. J. Phycol.
34: 16-28
Denovan-Wright, E.M.,
Nedelcu, A.M. and Lee, R.W. (1998) Complete sequence of the
mitochondrial DNA of Chlamydomonas eugametos. Plant
Mol. Biol. 36: 285-295
Nedelcu, A.M. (1997)
Fragmented and scrambled mitochondrial ribosomal RNA coding
regions among green algae: a model for their origin and
evolution. Mol. Biol. Evol. 14:506-517
Bussières, J., Lemieux, C., Lee, R.W.,
Turmel, M. (1996) Optional mobile genetic elements in the
chloroplast DNAs of Chlamydomonas eugametos and C.
moewusii: unidirectional gene conversions in high-viability
crosses. Curr. Genet. 30:356-365
Denovan-Wright, E.M.,
Sankoff, D. Spencer, D.F. and Lee, R.W. (1996) Evolution of
fragmented ribosomal RNA genes in Chlamydomonas. J. Mol. Evol.
42:382-391
Nedelcu, A. M.,
Spencer, D.F., Denovan-Wright, E.M. and Lee, R.W. (1996)
Discontinuous mitochondrial and chloroplast large subunit
ribosomal RNAs among green algae: phylogenetic implications.
J. Phycol. 32:103-111
Denovan-Wright, E.M.
and Lee, R.W. (1995) Evidence that the fragmented
ribosomal RNAs of Chlamydomonas mitochondria are
associated with ribosomes. FEBS Letters 370:222-226
Denovan-Wright, E..M.
and Lee, R.W. (1994) Comparative structure and genomic
organization of the discontinuous mitochondrial ribosomal RNA
genes of Chlamydomonas eugametos and Chlamydomonas
reinhardtii. J. Mol. Biol. 241:298-311
Denovan-Wright, E.M.
and Lee, R.W. (1993) Chlamydomonas eugametos
mitochondrial genome. In Genetic Maps, 6th Edition, Book 2,
Bacteria, Algae and Protozoa, S.J. O'Brien Ed.,
Denovan-Wright, E.M.
and Lee, R.W. (1992) Comparative analysis of the
mitochondrial genomes of Chlamydomonas eugametos and
Chlamydomonas moewusii. Curr. Genet. 21:197-202
Lee, R.W., Dumas, C. Lemieux, C. and
Turmel, M. (1991) Cloning and characterization of the
mitochondrial genome of Chlamydomonas moewusii. Mol.
Gen. Genetics 231:53-58
Lee, R.W. and Lemieux, C. (1990)
Loss of hybrid lethality during backcross programs involving
Chlamydomonas eugametos and Chlamydomonas moewusii (Chlorophyceae).
J. Phycol. 26, 376-380
Lee, R.W., B. Langille, C. Lemieux
and Boer, P.H. (1980) Inheritance of mitochondrial and
chloroplast genome markers in backcrosses of Chlamydomonas
eugametos X Chlamydomonas moewusii hybrids. Curr.
Genet. 17, 73-76
Lemieux, C. and Lee, R.W. (1987) Non-reciprocal recombination between alleles of the chloroplast 23S rRNA gene in interspecific Chlamydomonas crosses. Proc. Natl. Acad. Sci. USA 84, 4166-4170
Lee, R.W. and Lemieux, C. (1986)
Biparental inheritance of non-Mendelian gene markers in
Chlamydomonas moewusii. Genetics 113, 589-600
Turmel, M., G. Bellemare, R.W. Lee and
Lemieux, C. (1986) A linear DNA molecule of 5.9 kilobase-pairs
is highly homologous to the chloroplast DNA in the green alga
Chlamydomonas moewusii. Plant Mol. Biol. 6, 313-319
Vandermeulen, J.H. and Lee, R.W. (1986)
Lack of mutagenic activity of crude and refined oil in the
unicellular alga Chlamydomonas reinhardtii.
Bull. Env. Cont. Toxicol. 36, 250-253
Lemieux, C., M. Turmel,
R.W. Lee and Bellemare, G. (1985) A 21 kilobase-pair
deletion/addition difference in the inverted repeat sequence of
Chlamydomonas eugametos and C. moewusii chloroplast
DNA. Plant Mol. Biol. 5, 77-84
Boer, P.H., L. Bonen, R.W. Lee and Gray,
M.W. (1985) Genes for respiratory chain proteins and
ribosomal RNAs are present on a 16 kbp DNA species from
Chlamydomonas reinhardtii mitochondria. Proc. Natl. Acad.
Sci. USA 82, 3340-3344
Lemieux, C., M. Turmel,
V. Seligy and Lee, R.W. (l985) The large subunit of
ribulose-1,5-bisphosphate carboxylase-oxygenase is encoded
in the inverted repeat sequence of the Chlamydomonas
eugametos chloroplast genome. Curr.Genet. 9,
139-145
Lemieux, C., M. Turmel,
V. Seligy and Lee, R.W. (1984) A genetical approach to the
physical mapping of chloroplast genes in Chlamydomonas.
Lemieux, C., M. Turmel,
V. Seligy and Lee, R.W. (1984) Chloroplast DNA
recombination in interspecific hybrids of Chlamydomonas:
Linkage between a nonMendelian locus for streptomycin resistance
and restriction fragments coding for 16S rRNA. Proc. Natl.
Acad. Sci. USA 81, 1164-1168
Lemieux, C., M. Turmel
and Lee, R.W. (1981) Physical evidence for recombination
of chloroplast DNA in hybrid progeny of Chlamydomonas
eugametos and C. moewusii. Curr. Genet. 3,
97-103
Lemieux, C., M. Turmel
and Lee, R.W. (1982) Physical evidence for recombination
of chloroplast DNA in hybrid progeny of Chlamydomonas
eugametos and C. moewusii. Rosowski, J.R., Parker,
B.C. (eds.), Selected Papers in Phycology II. Allen Press
Turmel, M, C. Lemieux
and Lee, R.W. (1981) Dispersive labelling of
Chlamydomonas chloroplast DNA in 15N-14N
density transfer experiments. Curr. Genet. 4, 91-97
Lemieux, C., M. Turmel
and Lee, R.W. (1980) Characterization of chloroplast DNA
in Chlamydomonas eugametos and C. moewusii and its
inheritance in hybrid progeny. Curr. Genet. 2,
139-147
Turmel, M., C. Lemieux
and R.W. Lee (1980) Net synthesis of chloroplast DNA
throughout the synchronized cell-cycle of Chlamydomonas.
Curr. Genet. 2, 229-232
Lee, R.W. and Haughn, G.W. (1980)
Induction and segregation of chloroplast mutations in vegetative
cell cultures of Chlamydomonas reinhardtii. Genetics
96,79-94
Lee, R.W. and Sapp, J.A. (1978)
Nuclear mutation increases streptomycin and spectinomycin
sensitivity in Chlamydomonas. Genetics 88, 643-650
(1978).
Whiteway, M.S. and
Lee, R.W. (1977) Chloroplast DNA content increases with
nuclear ploidy in Chlamydomonas. Mol. Gen.
Genetics 157, 11-15
Lee, R.W. and Jones, R.F. (1976) Lethal
and mutagenic effects of nitrosoguanidine on synchronized
Chlamydomonas. Mol. Gen. Genetics 147, 283-289
Hawks, B.G. and Lee,
R.W. (1976) Methyl methanesulfonate mutagenesis of synchronized
Chlamydomonas. Mutation Res. 37, 222-228
Gillham, N.W., J.E. Boynton and Lee,
R.W. (1974) Segregation and recombination of non-Mendelian genes
in Chlamydomonas. Genetics 78, 439-457
Lee, R.W. and Jones, R.F. (1973)
Induction of Mendelian and non-Mendelian streptomycin resistant
mutants during the synchronous cell cycle of Chlamydomonas
reinhardtii. Mol. Gen. Genet.121, 99-108
Lee, R.W., N.W. Gillham, K.P. Van Winkle
and Boynton, J.E. (1973) Preferential recovery of uniparental
streptomycin resistant mutants from diploid Chlamydomonas
reinhardtii. Molec. Gen. Genetics
121, 109-116
Yentsch, C.S. and Lee, R.W. (1966) A
study of photosynthetic light reactions and a new interpretation
of sun and shade phytoplankton. J. of Marine Res. 24,
319-337
Wilce, R.T. and Lee, R.W. (1964)
Lomentaria clavellosa in